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Chitinase-3-like protein 1 Test Kit (Colloidal Gold)(Colloidal Gold Kit)
Product Description

✓ Dynamic and Accurate: CHI3L1 is the driving force of liver fibrogenesis, and dynamic assessment of progression/regression rate of liver fibrosis is better than the traditional static staging of fibrosis (stages 1-4). 

 ✓ Specific and Sensitive: CHI3L1 has high liver specificity. At the cut-off value of 79ng/ml, the specificity and sensitivity of CHI3L1 for moderate and severe liver fibrosis are both over 90%, higher than other diagnostic methods. 

✓ Non-invasive and Convenient: CHI3L1 is a stable serum biomarker whose level is not affected by ALT levels, ascites, serum bilirubin levels and other common factors. The diagnosis is non-invasive and is based on a single value from a single marker, which offers a safe and convenient method for fibrosis assessment.

Detection Principle
Immunohistochemical lateral flow technology as a platform on the test strip has solidified with the reagents and chromogenic materials analyte response. Double antibody sandwich immunoassay reaction principle, when chromogenic detection reagent and the sample reacting with the analyte to be cured, depending on the content of the subject matter presented at different depths of color after the reaction, the reaction is completed the colloidal gold HPJ-I immunoassay analyzer automatic interpretation of the results and display or print the report.
Product Performance

A novel diagnostic marker with increased sensitivity for advanced liver fibrosis. Good discrimination for different stages of liver fibrosis using CHI3L1. 

 Supported by publications from top universities (e.g. Harvard University) in high-ranking journals 

 Used by Lab Corp.-one of the largest diagnostic laboratory service provider in the United States 

 CE mark approval


Product Manual

A novel diagnostic marker with increased sensitivity for advanced liver fibrosis (cirrhosis)

Serum CHI3L1 levels were increased in alcoholic cirrhosis, post-hepatitic cirrhosis and non-cirrhotic fibrosis [6].
Several studies have established that CHI3L1 is a biomarker for HCV-induced liver fibrosis and cirrhosis [6-9].
CH13L1 was shown to be a biomarker for HBV-related liver fibrosis and cirrhosis [5].